I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Ionic liquids can effectively accelerate slow N-benzylation reactions utilizing dibenzyl carbonate as an alkylating reagent. Dibenzyl carbonate (DBzlC) has been used to benzylate phenylacetonitrile, benzyl phenylacetate and phenol. Selective N, N-dibenzylation of primary aliphatic amines was carried with dibenzyl carbonate in the presence of phosphonium salts.
Wen-Chung Shieh,; Mario Lozanov,; Oljan Repič. Accelerated benzylation reaction utilizing dibenzyl carbonate as an alkylating reagent. Tetrahedron Letters. 2003, 44 (36), 6943-6945.
Alessandro Loris,; Alvise Perosa,; Maurizio Selva,; Pietro Tundo. Selective N,N-Dibenzylation of Primary Aliphatic Amines with Dibenzyl Carbonate in the Presence of Phosphonium Salts. J. Org. Chem. 2004, 69 (11) , 3953-3956.
Benzylating agent, e.g. in preparation of benzyl ethers of thiols with K2CO3/ 18-crown-6: Synthesis, 382 (1986). Benzylation of phenols and monobenzylation of active methylene compounds have been accomplished using K2CO3 in DMF: J. Chem. Soc., Perkin 1, 1889 (1995). For N-, O- and S-benzylations in the presence of DBU or DABCO, see: Tetrahedron Lett., 44, 4563 (2003).
Hazard Statements: H302-H312
Harmful if swallowed. Harmful in contact with skin.
Precautionary Statements: P264b-P270-P280-P301+P312-P302+P352-P312-P330-P363-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant