Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

1734-79-8 - 4-Nitrocinnamaldehyde, predominantly trans, 98% - A11467 - Alfa Aesar

A11467 4-Nitrocinnamaldehyde, predominantly trans, 98%

CAS Number
1734-79-8
Synonyms

Size Price ($) Quantity Availability
5g 87.55
25g 312.30
50g 497.60
Add to Cart Add to Quote Request View Item

4-Nitrocinnamaldehyde, predominantly trans, 98%

MDL
MFCD00007379
EINECS
217-076-8

Chemical Properties

Formula
C9H7NO3
Formula Weight
177.16
Melting point
138-142°
Sensitivity
Air Sensitive
Solubility
Insoluble in water.

Applications

Doebner-Miller reaction the 4- nitrocinnamaldehyde and 2-methylaniline in concentrated HC1 give the corresponding 8-methyl-2-phenylquinoline (3: R = 4'-N02) directly. The asymmetric Friedel-Crafts-type alkylation in aqueous media reaction of 4-Nitrocinnamaldehydr with N-methyl indole using trifluoroacetic acid (TFA) salt of the PEG-PS-supported prolyl peptide having the polyleucine tether as a catalyst. 4-Nitrocinnamaldehyde has been used in the preparation of 2, 2?-[(E)-3-(4-nitrophenyl) prop-2-ene-1,1-diyl] bis(3-hydroxy-5, 5-dimethylcyclohex-2-en-1-one).

Notes

Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.

Literature References

Graham J. Atwell,; Bruce C. Baguley,; William A. Denny. Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as minimal DNA-intercalating antitumor agents with in vivo solid tumor activity . J. Med. Chem. 1989, 32(2),396-401.

Kengo Akagawa,; Takuhiro Yamashita,; Seiji Sakamoto,; Kazuaki Kudo. Friedel-Crafts-type alkylation in aqueous media using resin-supported peptide catalyst having polyleucine. Tetrahedron Letters. 2009, 50 (40) ,5602-5604.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
1565424
Harmonized Tariff Code
2913.00
TSCA
Yes
RTECS
GD6650000

Recommended

  • A10293

    1,4-Dinitrobenzene, 98+%
  • A10308

    2-Nitrocinnamaldehyde, predominantly trans, 98%
  • A10429

    alpha-Methylcinnamaldehyde, predominantly (E), 97%
  • A11655

    4-Nitrobenzaldehyde, 99%
  • A12839

    trans-4-Methoxycinnamaldehyde, 98+%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware