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68-94-0 - Hypoxanthine, 99% - 6-Hydroxypurine - A11481 - Alfa Aesar

A11481 Hypoxanthine, 99%

CAS Number
68-94-0
Synonyms
6-Hydroxypurine

Size Price ($) Quantity Availability
5g 19.62
25g 61.49
100g 185.07
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Hypoxanthine, 99%

MDL
MFCD00005725
EINECS
200-697-3

Chemical Properties

Formula
C5H4N4O
Formula Weight
136.11
Melting point
>300°
Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.

Applications

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. The compound has been used in studies as in indicator, along with uric acid and allantoin , of in vivo free radical reactions. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.

Literature References

Patrick A. Limbach.; Pamela F. Crain .; James A. McCloskey. the modified nucleosides of RNA. Oxford Journals. 1994, 22, (12), 2183-2196.

James S. Chickos .; William E. Acree Jr. Enthalpies of Sublimation of Organic and Organometallic Compounds. J. Phys. Chem.. 2002, 31, 537.

Other References

Merck
14,4869
Beilstein
5811
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UP0791000

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