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A11481 Hypoxanthine, 99%

CAS Number
68-94-0
Synonyms
6-Hydroxypurine

Stock No. Size Price ($) Quantity Availability
A11481-06 5g 23.30
A11481-14 25g 64.90
A11481-22 100g 204.00
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Hypoxanthine, 99%

MDL
MFCD00005725
EINECS
200-697-3

Chemical Properties

Formula
C5H4N4O
Formula Weight
136.11
Melting point
>300°
Storage & Sensitivity
Keep Cold.
Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.

Applications

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. The compound has been used in studies as in indicator, along with uric acid and allantoin , of in vivo free radical reactions. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.

Literature References

Patrick A. Limbach.; Pamela F. Crain .; James A. McCloskey. the modified nucleosides of RNA. Oxford Journals. 1994, 22, (12), 2183-2196.

James S. Chickos .; William E. Acree Jr. Enthalpies of Sublimation of Organic and Organometallic Compounds. J. Phys. Chem.. 2002, 31, 537.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,4869
Beilstein
5811
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UP0791000

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