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1-Chlorobutane is used as intermediates and solvents. It is used for HPLC, spectrophotometry and environmental testing. It is used as an alkylating reagent in organic and organometallic compound synthesis. It is also employed as an anthelmintic in veterinary medicine.
The Grignard reagent has been recommended as superior to EtMgBr for the preparation of ethynyl magnesium halides from acetylene. For details, see: Org. Synth. Coll., 8, 606 (1993); for generation and use of the Grignard in the Mn-Cu catalyzed 1,4-addition to an enone, see: Org. Synth. Coll., 9, 328 (1998).
Mututuvari, T. M.; Tran, C. D. Volumetric Study for the Binary Nitromethane with Chloroalkane Mixtures at Temperatures in the Range (298.15 to 318.15) K. J. Hazard. Mater. 2014, 264, 449-459.
Atanase, L. I.; Bistac, S.; Riess, G. Effect of poly(vinyl alcohol-co-vinyl acetate) copolymer blockiness on the dynamic interfacial tension and dilational viscoelasticity of polymer-anionic surfactant complex at the water-1-chlorobutane interface. Soft matter 2015, 11 (13), 2665-2672.
Hazard Statements: H225-H303
Highly flammable liquid and vapour. May be harmful if swallowed.
Precautionary Statements: P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Dispose of contents/container in accordance with local/regional/national/international regulations.