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Iminoacetic acid is used as an inhibitor of bovine liver glutamate dehydrogenase. It is used as a reagent in the synthesis of poly(N-isopropylacrylamide) (PNIPAM) microgel particles for metal affinity binding of peptides. It is mainly used for modulating peptide mobility by capillary electrophoresis. It is also used in chemotherapeutic treatment for metal poisoning. It acts as a tridendate ligand and forms metal complexes.
Deng, S.; Zhang, G.; Wang, X.; Zheng, T.; Wang, P. Preparation and performance of polyacrylonitrile fiber functionalized with iminodiacetic acid under microwave irradiation for adsorption of Cu (II) and Hg (II). Chem. Eng. J. 2015, 276, 349-357.
Loh, C. T.; Graham, B.; Abdelkader, E. H.; Tuck, K. L.; Otting, G. Generation of Pseudocontact Shifts in Proteins with Lanthanides Using Small Clickable Nitrilotriacetic Acid and Iminodiacetic Acid Tags. Chem. Eur. J. 2015, 21 (13), 5084-5092.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant