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121-60-8 - 4-Acetamidobenzenesulfonyl chloride, 98+% - N-Acetylsulfanilyl chloride - A11511 - Alfa Aesar

A11511 4-Acetamidobenzenesulfonyl chloride, 98+%

CAS Number
121-60-8
Synonyms
N-Acetylsulfanilyl chloride

Size Price ($) Quantity Availability
50g 14.11
250g 26.15
1000g 73.98
5000g 270.00
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4-Acetamidobenzenesulfonyl chloride, 98+%

MDL
MFCD00007442
EINECS
204-485-1

Chemical Properties

Formula
C8H8ClNO3S
Formula Weight
233.67
Melting point
ca 146° dec.
Sensitivity
Moisture Sensitive
Solubility
It is slightly in water. But soluble in benzene, chloroform and ether.

Applications

N-Acetylsulfanilyl chloride is used in the preparation of sulfanilamide and its derivatives which are intermediates to produce sulfa drugs. They are used in the prevention and treatment of bacterial infections, diabetes mellitus, edema, hypertension, and gout. It is also used as a Pharma raw material. N-Acetylsulfanilyl chloride widely used in the fields of dye, medicine, mainly used for preparation of Sulfanilamide, Sulfanilylureal, Sulfatolamide, Sulphathiourea , Sulfaguanidine and Sulfacetamide and etc.

Notes

Stable under ordinary conditions. Moisture sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents, Strong bases.

Literature References

Shinsaku Fujita.;  Kazuya Sano. Reduction of quinones and quinonemonosulfonimides with N,N-diethylhydroxylamine. J. Org. Chem. 1979, 44, (15), 2647-2651.

Richard E. Donaldson.; P. L. Fuchs. alpha.'-Functionalization of .beta.,.gamma.-unsaturated cyclohexenones. Utilization of silyl enol ethers produced from the lithium/ammonia reduction of silyl aryl ethers. J. Org. Chem. 1977, 42, (11), 2032-2034.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,103
Beilstein
746676
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2924.29
TSCA
Yes
RTECS
DB8837500

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