I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
It is widely used for a variety of roles in biology and medicine as a chelating therapy. It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths. These compounds are used as extractants for the separation of valuable metals or minerals including copper, lead, gold, other rare earth metals and kaolin. Hydroxamic acids are also used to produce corresponding isocyanates by dehydration followed by rearrangement reaction. It is also used as a common ligand utilized in the synthesis of metallacrowns.
Curt A. Davey & Roger E. Fenna. 2.3 Å Resolution X-ray Crystal Structure of the Bisubstrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase:? A Model for a Prereaction Complex with Hydrogen Peroxide. Biochemistry. 1996, 35, (33), 10967-10973.
Mark L. Stolowitz.; Clarence Ahlem.; Karin A. Hughes.; Robert J. Kaiser.; Edward A. Kesicki.; Guisheng Li.; Kevin P. Lund.; Steven M. Torkelson.; and Jean P. Wiley. Phenylboronic Acid-Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization. Bioconjugate Chem. 2001, 12, (2), 229-239.
Hazard Statements: H315-H319-H335-H341
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing genetic defects.
Precautionary Statements: P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P337+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant