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89-73-6 - Salicylhydroxamic acid, 99% - 2-Hydroxybenzohydroxamic acid - A11528 - Alfa Aesar

A11528 Salicylhydroxamic acid, 99%

CAS Number
89-73-6
Synonyms
2-Hydroxybenzohydroxamic acid

Size Price ($) Quantity Availability
10g 23.13
25g 41.49
50g 75.15
100g 141.30
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Salicylhydroxamic acid, 99%

MDL
MFCD00002110
EINECS
201-934-3

Chemical Properties

Formula
C7H7NO3
Formula Weight
153.14
Melting point
ca 170° dec.
Solubility
It is soluble in water.

Applications

It is widely used for a variety of roles in biology and medicine as a chelating therapy. It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths. These compounds are used as extractants for the separation of valuable metals or minerals including copper, lead, gold, other rare earth metals and kaolin. Hydroxamic acids are also used to produce corresponding isocyanates by dehydration followed by rearrangement reaction. It is also used as a common ligand utilized in the synthesis of metallacrowns.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong bases. Stable under normal conditions.

Literature References

Curt A. Davey & Roger E. Fenna. 2.3 Å Resolution X-ray Crystal Structure of the Bisubstrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase:? A Model for a Prereaction Complex with Hydrogen Peroxide. Biochemistry. 1996, 35, (33), 10967-10973.

Mark L. Stolowitz.; Clarence Ahlem.; Karin A. Hughes.; Robert J. Kaiser.; Edward A. Kesicki.; Guisheng Li.; Kevin P. Lund.; Steven M. Torkelson.; and Jean P. Wiley. Phenylboronic Acid-Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization. Bioconjugate Chem. 2001, 12, (2), 229-239.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H315-H319-H335-H303

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Precautionary Statements: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8331
Beilstein
1210520
Harmonized Tariff Code
2928.00
TSCA
No
RTECS
VO6870000

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