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Diphenylphosphinic acid is used as a reagent employed in the synthesis of bidentate ligands and peptide coupling agents.
Darrell Berlin, K.; Howard Austin, T.; Nagabhushanam, M. A Convenient Synthesis of Esters of Diphenylphosphinic Acid. III1,2. J. Org. Chem. 1965, 30, (4), 1267-1268.
Wm. A. Higgins.; Paul W. Vogel.; Craig, W.G. Aromatic Phosphinic Acids and Derivatives. I. Diphenylphosphinodithoic Acid and Its Derivatives. J. Am. Chem. Soc. 1955, 77, (7), 1864-1866.
Esters can be prepared by alkylation of the potassium salt in the presence of 18-Crown-6, A11249: Synthesis, 632 (1980).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.