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A11586 L-Phenylalaninol, 98%

CAS Number
3182-95-4
Synonyms
(S)-(-)-2-Amino-3-phenyl-1-propanol
H-Phe-ol

Stock No. Size Price ($) Quantity Availability
A11586-06 5g 87.50
A11586-14 25g 306.00
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L-Phenylalaninol, 98%

MDL
MFCD00004732
EINECS
221-674-4

Chemical Properties

Formula
C9H13NO
Formula Weight
151.21
Melting point
89-94°
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Soluble in chloroform, ethyl acetate, ethanol and methanol.

Applications

L-Phenylalaninol acts as an antiulcer agent that reduces the secretion of gastric acid and prevents ulcer formation. It inhibits intestinal absorption of L-phenylalanine making it a prospective treatment for phenylketonuria. Further, it reacts with nitriles to form oxazolines, which finds application in palladium-catalyzed allylic substitution. In addition to this, it is also used in amidation for chiral resolution and nicotinamide adenine dinucleotide modeling.

Notes

Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Literature References

Shi, Z.; Xiao, X.; Mao, D.; Lu, G. Effects of the preparation method on the performance of the Cu/ZnO/Al2O3 catalyst for the manufacture of L-phenylalaninol with high ee selectivity from L-phenylalanine methyl ester. Catal. Sci. Technol. 2014, 4 (4), 1132-1143.

Liu, X.; Hu, L.; Jiang, L.; Jia, J.; Zhang, D.; Chen, X. Asymmetric Synthesis of Concentricolide. Eur. J. Org. Chem. 2015, 2015 (10), 2291-2296.

GHS Hazard and Precautionary Statements

Hazard Statements: H314

Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2208238
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2922.19
TSCA
No
RTECS
UA6900000

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