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1,2,4-Triazole is widely used as an intermediate in the manufacture of pharmaceuticals. It acts as an anti-scaling agent and antifungal compound. It is widely used in antifungals such as fluconazole anditraconazole.
Feldman, J.; Vo, G. D.; McLaren, C. D.; Gehret, T. C.; Park, K.; Meth, J. S.; Marshall, W. J.; Buriak, J.; Bryman, L. M.; Dobbs, K. D.; Scholz, T. H.; Zane, S. G. Highly Quantum Efficient Phosphorescent Sky Blue Emitters Based on Diastereomeric Iridium(III) Complexes of Atropisomeric 5-Aryl-4H-1,2,4-triazole Ligands. Organometallics 2015, 34 (15), 3665-3669.
Bennion, J. C.; McBain, A.; Son, S. F.; Matzger, A. J. Design and Synthesis of a Series of Nitrogen-Rich Energetic Cocrystals of 5,5'-Dinitro-2H,2H'-3,3'-bi-1,2,4-triazole (DNBT). Cryst. Growth Des. 2015, 15 (5), 2545-2549.
Hazard Statements: H302-H319-H361d
Harmful if swallowed. Causes serious eye irritation. Suspected of damaging the unborn child.
Precautionary Statements: P201-P202-P264b-P270-P280i-P281-P301+P312-P305+P351+P338-P308+P313-P330-P337+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear eye/face protection. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If eye irritation persists: Dispose of contents/ container to an approved waste disposal plant