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1,2,4-Triazole is widely used as an intermediate in the manufacture of pharmaceuticals. It acts as an anti-scaling agent and antifungal compound. It is widely used in antifungals such as fluconazole anditraconazole.
Feldman, J.; Vo, G. D.; McLaren, C. D.; Gehret, T. C.; Park, K.; Meth, J. S.; Marshall, W. J.; Buriak, J.; Bryman, L. M.; Dobbs, K. D.; Scholz, T. H.; Zane, S. G. Highly Quantum Efficient Phosphorescent Sky Blue Emitters Based on Diastereomeric Iridium(III) Complexes of Atropisomeric 5-Aryl-4H-1,2,4-triazole Ligands. Organometallics 2015, 34 (15), 3665-3669.
Bennion, J. C.; McBain, A.; Son, S. F.; Matzger, A. J. Design and Synthesis of a Series of Nitrogen-Rich Energetic Cocrystals of 5,5'-Dinitro-2H,2H'-3,3'-bi-1,2,4-triazole (DNBT). Cryst. Growth Des. 2015, 15 (5), 2545-2549.
Hazard Statements: H302-H319-H361
Harmful if swallowed. Causes serious eye irritation. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P201-P280-P305+P351+P338-P301+P312a-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.