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1,4-Dibromobutane is used as an intermediate involved in the synthesis of active pharmaceutical ingredient and other organic compounds. It is also used in the investigation of metabolism of two halopropanes such as 1,3-dichloropropane and 2,2-dichloropropane. Further, it acts as a reagent to prepare diazadioxa oxovanadium(IV) macrocyclic complexes.
Chen, J.; Li, N.; Gao, Y.; Sun, F.; He, J.; Li, Y. Dual-responsive polypseudorotaxanes based on block-selected inclusion between polyethylene-block-poly(ethylene glycol) diblock copolymers and 1,4-diethoxypillararene. Soft matter 2015, 11 (39), 7835-7840.
Stehouwer, J. S.; Goodman, M. M. Preparation of 1-tosyloxy-4-substituted-2-butenes using Ag(I) salts. Tetrahedron lett. 2015, 56 (30), 4480-4482.
Hazard Statements: H301-H315-H318-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.