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Diethylamine is used as a corrosion inhibitor. It is also used in the production of rubber, resins, dyes and pharmaceuticals.
Alkali metal diethylamides, generated with n-BuLi or NaH, have been used for the cleavage of ethers: J. Organomet. Chem., 55, 41 (1973); Synthesis, 638 (1980), and of alkyl aryl sulfides, for which HBr and HI are usually poor: Synthesis, 583 (1982).
In combination with Lithium aluminum hydride, A18116, generates lithium tris(diethylamino)aluminum hydride, which is a useful selective reducing agent, for example: esters to aldehydes: J. Org. Chem., 52, 5486 (1987); amides to aldehydes: Tetrahedron Lett., 32, 6903 (1991).
Wang, N. N.; Zhang, D. L.; Jiang, X. H. Detection of Xeljanz Enantiomers in Diethyl Amine Active Pharmaceutical Ingredients and Tablets. Chirality 2015, 27 (3), 235-238.
Higashino, T.; Soya, T.; Kim, W.; Kim, D.; Osuka, A. A Mobius Aromatic Hexaphyrin Bearing a Diethylamine Group: A Rigid but Smooth Conjugation Circuit. Angew. Chem. Int. Ed. 2015, 54 (18), 5456-5459.
Hazard Statements: H225-H302-H311-H314-H332-H335
Highly flammable liquid and vapour. Harmful if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Harmful if inhaled. May cause respiratory irritation.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.