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A11848 Hexamethyldisiloxane, 98+%

CAS Number
107-46-0
Synonyms
HMDSO

Stock No. Size Price ($) Quantity Availability
A11848-AE 100ml 21.50
A11848-AP 500ml 74.00
A11848-0F 2500ml 304.00
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Hexamethyldisiloxane, 98+%

MDL
MFCD00008265
EINECS
203-492-7

Chemical Properties

Formula
C6H18OSi2
Formula Weight
162.38
Melting point
-67°
Boiling Point
100-101°
Flash Point
-2°(28°F)
Density
0.764
Refractive Index
1.3770
Storage & Sensitivity
Ambient temperatures.
Solubility
Slightly miscible with water.

Applications

Hexamethyldisiloxane is used as a solvent in organic reactions. It finds application as an international standard for 1H NMR spectroscopy for calibrating chemical shift. Further, it is used in liquid bandages to protect skin from irritation. In addition, it is used to measure tissue oxygen tension as a receptor molecule. It is also used to make low-k dielectric materials for the semi-conductor industries by plasma-enhanced chemical vapor deposition(PECVD) method.

Notes

Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acids, bases and oxygen.

Literature References

Silylates primary and sec-alcohols and phenols, in the presence of p-TsOH as catalyst. If the substrate contains acid-sensitive groups, PPTS can be used: Tetrahedron Lett., 4261 (1978). See Appendix 4.

In the presence of FeCl3, reacts with benzotrichlorides to give substituted benzoyl chlorides in good yields: J. Chem. Soc., Chem. Commun., 808 (1977).

Reacts with P2O5 to give trimethylsilyl polyphosphate ('PPSE'), a milder and more convenient dehydrating agent then polyphosphoric acid. For examples, and related reagents, see Phosphorus(V)­ oxide, A13348.

Bashir, M.; Bashir, S. Hydrophobic-Hydrophilic Character of Hexamethyldisiloxane Films Polymerized by Atmospheric Pressure Plasma Jet. Plasma Chem. Plasma Process 2015, 35 (4), 739-755.

Hsiao, C. R.; Lin, C. W.; Chou, C. M.; Chung, C. J.; He, J. L. Surface modification of blood-contacting biomaterials by plasma-polymerized superhydrophobic films using hexamethyldisiloxane and tetrafluoromethane as precursors. Appl. Surf. Sci. 2015, 346, 50-56.

GHS Hazard and Precautionary Statements

Hazard Statements: H225

Highly flammable liquid and vapour.

Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P271-P280-P303+P361+P353-P304+P340-P312-P314-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1736258
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2931.90
TSCA
Yes
RTECS
JM9237000

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