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51-35-4 - trans-4-Hydroxy-L-proline, 99+% - (2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid - H-Hyp-OH - A11851 - Alfa Aesar

A11851 trans-4-Hydroxy-L-proline, 99+%

CAS Number
51-35-4
Synonyms
(2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid
H-Hyp-OH

Size Price ($) Quantity Availability
10g 30.78
25g 61.20
100g 173.70
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trans-4-Hydroxy-L-proline, 99+%

MDL
MFCD00064320
EINECS
200-091-9

Chemical Properties

Formula
C5H9NO3
Formula Weight
131.13
Melting point
270-273° dec.
Solubility
Soluble in water.

Applications

trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

Notes

Incompatible with strong oxidizing agents.

Literature References

Chiral precursor for a wide variety of synthetic targets. For discussion of some examples, see: Tetrahedron, 52, 13803 (1996).

Satomura, T.; Ishikura, M.; Koyanagi, T.; Sakuraba, H.; Ohshima, T.; Suye, S. I. Dye-linked d-amino acid dehydrogenase from the thermophilic bacterium Rhodothermus marinus JCM9785: characteristics and role in trans-4-hydroxy-l-proline catabolism. Appl. Microbiol. Biotechnol. 2015, 99 (10), 4265-4275.

Kuttan, R.; Panikkar, B.; Binitha, P. P. Amino acids in sandal (Santalum album L) with special reference to cis-4-hydroxy-l-proline and sym. homospermidine. Springerplus 2015, 4 (1), 1-9.

Other References

Merck
14,4840
Beilstein
471933
Harmonized Tariff Code
2933.99
TSCA
Yes
RTECS
TW3586500

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