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1,4-Dichloro-2-nitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. It is also used in the synthesis of lysophosphatidic acid acyltransferase-β in hibitors.
Makoto Ohnishi; Kazunori Yamazaki; Seigo Yamamoto; Taijiro Matsushima. Characterization of N-Acetylcysteine Conjugate in Yellow Urine by Oral Administration of 1,4-Dichloro-2-Nitrobenzene in Rats.Journal of Health Science. 2004, 50 319-322.
Kumar; J Senthil; Arivazhagan M. DFT and ab-initio study of structure of 1,4-dichloro-2-nitrobenzene.Indian Journal of Pure & Applied Physics. 2011, 49 673-678.
Hazard Statements: H302-H319-H341
Harmful if swallowed. Causes serious eye irritation. Suspected of causing genetic defects.
Precautionary Statements: P273-P280h-P305+P351+P338
Avoid release to the environment. Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.