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1,3-Propane sultone is used as a chemical intermediate to introduce sulfopropyl groups into molecules and to confer water solubility and anionic character.
Laurent Hortala.; Christina Moberg.; Vincent Levacher.; Jean Bourguignon.; Georges Dupas. Acyl transfer of 8-acetoxy-2-oxazolinylquinoline assisted by hydrogen bonding formation.Tetrahedron Lett.2002,43/span>(6), 1027-1029.
Mitsuyasu Kawahara.; Masahiro Rikukawa.; Kohei Sanui.; Naoya Ogata. Synthesis and proton conductivity of sulfopropylated poly(benzimidazole) films.Solid State Ionics,2000,136-137/span>(2), 1193-1196.
For a review of the chemistry of sultones, see: Tetrahedron, 43, 1027 (1987).
Hazard Statements: H302+H312-H350
Harmful if swallowed. Harmful in contact with skin. May cause cancer.
Precautionary Statements: P201-P202-P264b-P270-P281-P301+P312-P302+P352-P308+P313-P312-P330-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant