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533-67-5 - 2-Deoxy-D-ribose, 99% - Thyminose - A11990 - Alfa Aesar

A11990 2-Deoxy-D-ribose, 99%

CAS Number
533-67-5
Synonyms
Thyminose

Size Price ($) Quantity Availability
1g 18.44
5g 59.35
25g 176.40
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2-Deoxy-D-ribose, 99%

MDL
MFCD00135904
EINECS
208-573-0

Chemical Properties

Formula
C5H10O4
Formula Weight
134.13
Melting point
76-85°
Sensitivity
Hygroscopic
Solubility
Soluble in water.

Applications

2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Notes

Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Starting material for a free-radical coupling reaction (employing homolytic fission of a derivative with 2-Mercaptopyridine N-oxide, A14152) which provides a facile preparative method for C-nucleosides: Chem. Lett., 1673 (1992).

Koh, G.; Yang, E. J.; Kim, J. Y.; Hyun, J.; Yoo, S.; Lee, S. A. Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2?deoxy?D?ribose?induced beta?cell damage. Mol. Med. Rep. 2015, 12 (4), 5314-5320.

Azofra, L. M.; Quesada-Moreno, M. M.; Alkorta, I.; Avilés-Moreno, J. R.; López-González, J. J.; Elguero, J. Carbohydrates in the gas phase: conformational preference of d-ribose and 2-deoxy-d-ribose. New J. Chem. 2014, 38 (2), 529-538.

Other References

Merck
14,2908
Beilstein
1721978
Harmonized Tariff Code
2940.00
TSCA
Yes
RTECS
SB7230000

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