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4178-93-2 - L-Leucine-4-nitroanilide, 99% - A11994 - Alfa Aesar

A11994 L-Leucine-4-nitroanilide, 99%

CAS Number
4178-93-2
Synonyms

Size Price ($) Quantity Availability
1g 34.11
5g 155.53
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L-Leucine-4-nitroanilide, 99%

MDL
MFCD00063681
EINECS
224-047-3

Chemical Properties

Formula
C12H17N3O3
Formula Weight
251.29
Melting point
89-90°
Solubility
Soluble in DMSO (>100 mM), and methanol (>25 mM).

Applications

It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.

Notes

Store away from oxidizing agents. Keep the container tightly closed in a well ventilated place.

Literature References

A Bernkop-Schnürch.; M K Marschütz. Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N.Pharm. Res.1997,14(2), 181-185.

E K Deniakina.; A D Nekliudov.; T A Loginova.; I A Krest'ianova.; Iu E Bartoshevich. Production and properties of an immobilized enzyme preparation with peptidase activity.Prikl Biokhim Mikrobiol.1985,21(2), 177-83.

Other References

Beilstein
2218433
Harmonized Tariff Code
2924.29
TSCA
Yes

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