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A12026 2-Aminothiazole, 97%

CAS Number
96-50-4
Synonyms

Stock No. Size Price ($) Quantity Availability
A12026-18 50g 19.60
A12026-22 100g 26.30
A12026-30 250g 49.80
A12026-36 500g 87.40
A12026-0E 2500g 353.00
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2-Aminothiazole, 97%

MDL
MFCD00005325
EINECS
202-511-6

Chemical Properties

Formula
C3H4N2S
Formula Weight
100.14
Melting point
88-92°
Boiling Point
117°/15mm
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water, alcohol and ether.

Applications

2-Aminothiazole is used in the synthesis of 2-aminothiazole-modified silica gel and also used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation. It acts as a component of disperse dye, thyroid inhibitor in the treatment of hyperthyroidism, as the acid tartrate and as a therapeutic drug for prion diseases. It is also used to kill bacteria.

Notes

Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, nitric acid and sulfuric acid.

Literature References

Yadav, P.; Dutta, P. K.; Ballabh, A. Combinatorial Library Approach to Realize 2-Aminothiazole-Based Two-Component Hydrogelator: A Structure-Property Correlation.Cryst. Growth Des. 2014, 14 (11), 5966-5975.

Xiong, C.; Zhou, S.; Liu, X.; Jia, Q.; Ma, C.; Zheng, X. 2-Aminothiazole Functionalized Polystyrene for Selective Removal of Au(III) in Aqueous Solutions. Ind. Eng. Chem. Res. 2014, 53 (6), 2441-2448.

Xiong, C.; Jia, Q.; Chen, X.; Wang, G.; Yao, C. Optimization of Polyacrylonitrile-2-aminothiazole Resin Synthesis, Characterization, and Its Adsorption Performance and Mechanism for Removal of Hg(II) from Aqueous Solutions. Ind. Eng. Chem. Res. 2013, 52 (14), 4978-4986.

Giles, K.; Berry, D. B.; Condello, C.; Hawley, R. C.; Gallardo-Godoy, A.; Bryant, C.; Oehler, A.; Elepano, M.; Bhardwaj, S.; Patel, S.; Silber, M.; Guan, S.; Armond, S. J.; Renslo, A. R.; Prusiner, S. B. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J. Pharmacol. Exp. Ther. 2015, 355 (1), 2-12.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H319-H335

Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280i-P301+P312-P304+P340-P305+P351+P338-P312-P330-P337+P313-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear eye/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,479
Beilstein
105738
Harmonized Tariff Code
2934.10
TSCA
Yes
RTECS
XJ2100000

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