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96-50-4 - 2-Aminothiazole, 97% - A12026 - Alfa Aesar

A12026 2-Aminothiazole, 97%

CAS Number
96-50-4
Synonyms

Size Price ($) Quantity Availability
50g 18.80
100g 25.80
250g 47.90
500g 85.80
2500g 343.00
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2-Aminothiazole, 97%

MDL
MFCD00005325
EINECS
202-511-6

Chemical Properties

Formula
C3H4N2S
Formula Weight
100.14
Melting point
88-92°
Boiling Point
117°/15mm
Solubility
Soluble in water, alcohol and ether.

Applications

2-Aminothiazole is used in the synthesis of 2-aminothiazole-modified silica gel and also used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation. It acts as a component of disperse dye, thyroid inhibitor in the treatment of hyperthyroidism, as the acid tartrate and as a therapeutic drug for prion diseases. It is also used to kill bacteria.

Notes

Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, nitric acid and sulfuric acid.

Literature References

Yadav, P.; Dutta, P. K.; Ballabh, A. Combinatorial Library Approach to Realize 2-Aminothiazole-Based Two-Component Hydrogelator: A Structure-Property Correlation.Cryst. Growth Des. 2014, 14 (11), 5966-5975.

Xiong, C.; Zhou, S.; Liu, X.; Jia, Q.; Ma, C.; Zheng, X. 2-Aminothiazole Functionalized Polystyrene for Selective Removal of Au(III) in Aqueous Solutions. Ind. Eng. Chem. Res. 2014, 53 (6), 2441-2448.

Xiong, C.; Jia, Q.; Chen, X.; Wang, G.; Yao, C. Optimization of Polyacrylonitrile-2-aminothiazole Resin Synthesis, Characterization, and Its Adsorption Performance and Mechanism for Removal of Hg(II) from Aqueous Solutions. Ind. Eng. Chem. Res. 2013, 52 (14), 4978-4986.

Giles, K.; Berry, D. B.; Condello, C.; Hawley, R. C.; Gallardo-Godoy, A.; Bryant, C.; Oehler, A.; Elepano, M.; Bhardwaj, S.; Patel, S.; Silber, M.; Guan, S.; Armond, S. J.; Renslo, A. R.; Prusiner, S. B. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J. Pharmacol. Exp. Ther. 2015, 355 (1), 2-12.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,479
Beilstein
105738
Harmonized Tariff Code
2934.10
TSCA
Yes
RTECS
XJ2100000

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