Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

7080-50-4 - Chloramine-T trihydrate, 98% - N-Chloro-p-toluenesulfonamide sodium salt trihydrate - Tosylchloramide sodium trihydrate - A12044 - Alfa Aesar

A12044 Chloramine-T trihydrate, 98%

CAS Number
7080-50-4
Synonyms
N-Chloro-p-toluenesulfonamide sodium salt trihydrate
Tosylchloramide sodium trihydrate

Size Price ($) Quantity Availability
250g 24.79
1000g 70.11
5000g 232.80
Add to Cart Add to Quote Request View Item

Chloramine-T trihydrate, 98%

MDL
MFCD00149066
EINECS
204-854-7

Chemical Properties

Formula
C7H7ClNNaO2S•3H2O
Formula Weight
281.69 (227.67anhy)
Melting point
167-170°
Flash Point
192°(377°F)
Sensitivity
Moisture Sensitive
Solubility
Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.

Applications

Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).

Notes

Incompatible with strong oxidizing agents, acids and ammonia.

Literature References

Mal, S.; Prathap, K. J.; Smith, S. C.; Umarye, J. D. Facile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T. Tetrahedron Lett. 2015, 56 (22), 2896-2901.

Dzandzi, J. P. K.; Vera, D. R. B.; Genady, A. R.; Albu, S. A.; Eltringham-Smith, L. J.; Capretta, A.; Sheffield, W.P.; Valliant, J. F. Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis. J. Org. Chem. 2015, 80 (14), 7117-7125.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H314-H318-H302

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed.

Precautionary Statements: P260-P285-P261-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2075
Beilstein
3924168
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2935.00
TSCA
Yes
RTECS
XT5616800

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware