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It is a caffeine metabolite which showed high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee. an be used to inhibit prostaglandin E(2) production.
Andreas R Rechner.; Jeremy P.E Spencer.; Gunter Kuhnle.; Ulrich Hahn.; Catherine A Rice-Evans. Novel biomarkers of the metabolism of caffeic acid derivatives in vivo.Free Radical Biol. Med. 2001, 30 (11),1213-1222.
D. F. Sharman. A Fluorimetric Method For The Estimation Of 4-Hydroxy-3-Methoxyphenylacetic Acid (Homovanillic Acid) And Its Identification In Brain Tissue. British Journal of Pharmacology and Chemotherapy. 1963, 20 (1),204-213.
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.