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637-01-4 - N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+% - 1,4-Bis(dimethylamino)benzene dihydrochloride - Wurster's Blue dihydrochloride - A12107 - Alfa Aesar

A12107 N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%

CAS Number
637-01-4
Synonyms
1,4-Bis(dimethylamino)benzene dihydrochloride
Wurster's Blue dihydrochloride

Size Price ($) Quantity Availability
10g 48.88
50g 179.22
250g 587.20
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N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%

MDL
MFCD00012482
EINECS
211-274-8

Chemical Properties

Formula
C10H16N2•2HCl
Formula Weight
237.17
Melting point
ca 228° dec.
Sensitivity
Light Sensitive
Solubility
Soluble in dimethyl sulfoxide, water and phosphate buffered saline at pH 7.2.

Applications

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

Notes

Light sensitive. Incompatible with strong oxidizing agents.                    

Literature References

Zoll, J.; Bouitbir, J.; Sirvent, P.; Klein, A.; Charton, A.; Jimenez, L.; Péronnet, F. R.; Geny, B.; Richard, R. apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection. Drug Des. Devel. Ther. 2015, 9, 3589-3597.

Lejay, A.; Choquet, P.; Thaveau, F.; Singh, F.; Schlagowski, A.; Charles, A. L.; Laverny, G.; Metzger, D.; Zoll, J.; Chakfe, N. A New Murine Model of Sustainable and Durable Chronic Critical Limb Ischemia Fairly Mimicking Human Pathology. Eur. J. Vasc. Endovasc. 2015, 49 (2), 205-212.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
5132096
Harmonized Tariff Code
2921.51
TSCA
Yes

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