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4-Iodoanisole is used in wide range of medicals industrial applications as well as in human and animal nutrition products, pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals. Iodine derivatives are also used as organic building blocks, analytical reagents.
Noel S. Murcia; Dennis G. Peters. Electroreductive carboxylation of halobenzenes. Production of p-anisic acid by reduction of p-iodoanisole at mercury in dimethylformamide saturated with carbon dioxide. J. Electroanal. Chem. 1992, 326 (1-2), 69-79.
Gertrude Maud Robinson. LXXVII.Experiments on the so-called migration of atoms and groups. Part I. The nitration of p-iodoanisole and other iodo-phenolic ethers. J. Chem. Soc., Trans. 1916, 109, 1078-1091.
For use in the 'ligandless' Suzuki cross-coupling with arylboronic acids, see: Org. Synth., 75, 61 (1997).