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Pyridine-2,6-dicarboxylic acid is used in the preparation of dipicolinato ligated lanthanide and transition metal complexes. It acts as a chelating agent for chromium, zinc, manganese, copper, iron and molybdenum. Its calcium-dipcolinic acid complex is used to protect deoxyribonucleic acid (DNA) from heat denaturation which enhances the DNA stability. It plays an important role as a marker for the effectiveness of sterilization.
Ge, J.; Yang, Q.; Xie, G.; Chen, S.; Gao, S. Synthesis, structure and thermochemical study of a cobalt energetic coordination compound incorporating 3, 5-diamino-1, 2, 4-triazole and pyridine-2, 6-dicarboxylic acid. J. Chem. Thermodyn. 2015, 80, 1-6.
Mohammadi, S.; Khayatian, G. Colorimetric detection of Bi(III) in water and drug samples using pyridine-2, 6-dicarboxylic acid modified silver nanoparticles. Spectrochim. Acta, Part A 2015, 148, 405-411.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant