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Phthalazine derivatives including copper and platinum complexes were induce the apoptosis in breast cancer cell lines and renal hyperemia.
Jamal M Arif; Muhammad Kunhi; Adnan A Bekhit; Manogaran P Subramanian; Khalid Al-Hussein; Hassan Y Aboul-Enein; Fahad M Al-Khodairy. Evaluation of apoptosis-induction by newly synthesized phthalazine derivatives in breast cancer cell lines. Asian Pacific journal of cancer prevention. 2006, 7 (2), 249-252.
Reubi, F. C. Renal Hyperemia Induced in Man by a New Phthalazine Derivative. Exp Biol Med. 1950, 73 (1), 102-103.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant