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A12370 Sulfadiazine, 99%

CAS Number
68-35-9
Synonyms
N(1)-(2-Pyrimidinyl)sulfanilamide

Stock No. Size Price ($) Quantity Availability
A12370-18 50g 17.70
A12370-30 250g 59.10
A12370-0B 1000g 198.00
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Sulfadiazine, 99%

MDL
MFCD00006065
EINECS
200-685-8

Chemical Properties

Formula
C10H10N4O2S
Formula Weight
250.28
Melting point
253-256°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in dimethyl sulfoxide.

Applications

Sulfadiazine is used as an antibacterial. It is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections and to control acute infections when studying murine models of reactivated toxoplasmosis. It is It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs)

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Charles L. Fox Jr.; Shanta M. Modak. Mechanism of Silver Sulfadiazine Action on Burn Wound Infections. Antimicrob. Agents Chemother. 1974, 5 (6), 582-588.

Shanta M. Modak.; Charles L. Fox Jr. Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa. Biochemical Pharmacology. 1973, 22 (19), 2391-2404.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H317-H319-H334-H335

Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P272-P280-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P333+P313-P337+P313-P342+P311-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8903
Harmonized Tariff Code
2935.90
TSCA
Yes
RTECS
WP1925000

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