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68-35-9 - Sulfadiazine, 99% - N(1)-(2-Pyrimidinyl)sulfanilamide - A12370 - Alfa Aesar

A12370 Sulfadiazine, 99%

CAS Number
68-35-9
Synonyms
N(1)-(2-Pyrimidinyl)sulfanilamide

Size Price ($) Quantity Availability
50g 16.75
250g 55.62
1000g 145.60
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Sulfadiazine, 99%

MDL
MFCD00006065
EINECS
200-685-8

Chemical Properties

Formula
C10H10N4O2S
Formula Weight
250.28
Melting point
253-256°
Solubility
Soluble in dimethyl sulfoxide.

Applications

Sulfadiazine is used as an antibacterial. It is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections and to control acute infections when studying murine models of reactivated toxoplasmosis. It is It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs)

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Charles L. Fox Jr.; Shanta M. Modak. Mechanism of Silver Sulfadiazine Action on Burn Wound Infections. Antimicrob. Agents Chemother. 1974, 5 (6), 582-588.

Shanta M. Modak.; Charles L. Fox Jr. Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa. Biochemical Pharmacology. 1973, 22 (19), 2391-2404.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H315-H319-H317-H302-H335

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. Harmful if swallowed. May cause respiratory irritation.

Precautionary Statements: P285-P261-P280-P305+P351+P338-P304+P340-P342+P311-P362-P301+P312-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8903
Harmonized Tariff Code
2935.00
TSCA
Yes
RTECS
WP1925000

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