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L-Histidine methyl ester dihydrochloride is used to prepare optically pure L-(+)-ergothioneine.
Vilchiz, V. H.; Norman, R. E.; Chang, S. C. L-Histidine methyl ester dihydrochloride. Acta Crystallographica Section C: Crystal Structure Communications. 1998, 52 (3), 696-698.
Gonsago, C. A.; Albert, H. M.; Malliga, P.;Pragasam, A. J. A. Crystallization, spectral, and thermal characterization of l-histidine methyl ester dihydrochloride (LHMED). Journal of thermal analysis and calorimetry. 2011, 107 (3), 1231-1235.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant