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3612-20-2 - 1-Benzyl-4-piperidone, 98+% - A12390 - Alfa Aesar

A12390 1-Benzyl-4-piperidone, 98+%

CAS Number
3612-20-2
Synonyms

Size Price ($) Quantity Availability
25g 29.50
100g 97.10
500g 352.00
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1-Benzyl-4-piperidone, 98+%

MDL
MFCD00006192
EINECS
222-782-4

Chemical Properties

Formula
C12H15NO
Formula Weight
189.26
Boiling Point
248°
Flash Point
>110°(230°F)
Density
1.059
Refractive Index
1.5399
Solubility
Soluble in water (12 g/100ml at 20°C).

Applications

1-Benzyl-4-piperidone is a pharmaceutical intermediate, it is used in penfluridol synthesis of bulk drugs.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Christie Morrill.; Neelakandha S. Mani. Synthesis of 4-Arylpiperidines from 1-Benzyl-4-piperidone:? Application of the Shapiro Reaction and Alkenylsilane Cross-Coupling. Org. Lett. 2007, 9 (8), 1505-1508.

Chunmei Gao.; Yuyang Jiang.; Chunyan Tan.; Xuyu Zu.; Huachen Liu.; Derong Cao. Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones. Bioorganic & Medicinal Chemistry. 2008, 16 (18), 8670-8675.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
128556
Harmonized Tariff Code
2933.39
TSCA
No

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