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Sodium cyanate is an ideal nucleophile, and these nucleophilic properties make it a major contributor to the stereospecificity in certain reactions such as in the production of chiral oxazolidone. Sodium cyanate is a useful reagent in producing asymmetrical urea that have a range of biological activity mostly in aryl isocyanate intermediates. Such intermediates as well as sodium cyanate have been used in medicine as a means of counterbalancing carcinogenic effects on the body.
R. Badera,; D.J. Dupréa,; F. Schütz. The preparation of pure sodium cyanate from urea. Biochimica et Biophysica Acta. 1948, 2 543-548.
Gavin Chit Tsui et. al. Expedient synthesis of chiral oxazolidinone scaffolds via rhodium-catalyzed asymmetric ring-opening with sodium cyanate.. Organic Letters. 2013, 15 (5),1064-1067.
Hazard Statements: H302
Harmful if swallowed.
Precautionary Statements: P264-P270-P301+P312a-P330-P501a
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.