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It is used as the reagent for the derivatization of amines, alcohols, etc., for GC purposes. It has been utilized for dual element acetylation tagging derivatization of amines by using microwave sustained helium emission detector1 and as a derivatization reagent in determination of estrone and 17β-estradiol in hair by GC-MS2.
D.F. Hagen.; J.S. Marhevka.; L.C. Haddad. Multi-element taggant and dual homolog derivatization concepts in GC/MED. Spectrochim. Acta, Part B . 1985, 40 (1-2),335-347.
Donald F. Hagen.; Louis C. Haddad.; John S. Marhevka. Solution and gas phase deuterium derivatization reactions for gas chromatography/microwave emission detection.Spectrochim. Acta, Part B . 1987, 42 (1-2), 253-267.
Reagent for the derivatization of amines, alcohols, etc., for GC purposes.
Hazard Statements: H314-H335
Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant