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1,8-Diazabicyclo[5.4.0]undec-7-ene is used in organic synthesis as a catalyst, a complexing ligand, and a non-nucleophilic base. It is used as a protecting agent for the synthesis of cephalosporin and as a catalyst for polyurethane.
Zheng, J.; Lin, J.; Deng, X.; Xiao, J. 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-Promoted Decomposition of Difluorocarbene and the Subsequent Trifluoromethylation. Org. Lett. 2015, 17 (3), 532-535.
Singh, V.; Singh, D.; Gardas, R. L. Effect of DBU (1,8-Diazobicyclo[5.4.0]undec-7-ene) Based Protic Ionic Liquid on the Volumetric and Ultrasonic Properties of Ascorbic Acid in Aqueous Solution. Ind. Eng. Chem. Res. 2015, 54 (7), 2237-2245.
Hazard Statements: H301-H314-H335
Toxic if swallowed. Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant