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54-96-6 - 3,4-Diaminopyridine, 98+% - 3,4-Pyridinediamine - A12465 - Alfa Aesar

A12465 3,4-Diaminopyridine, 98+%

CAS Number
54-96-6
Synonyms
3,4-Pyridinediamine

Size Price ($) Quantity Availability
1g 34.30
5g 121.54
25g 366.40
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3,4-Diaminopyridine, 98+%

MDL
MFCD00006401
EINECS
200-220-9

Chemical Properties

Formula
C5H7N3
Formula Weight
109.13
Melting point
217-220°
Flash Point
240°(464°F)
Solubility
Soluble in water (24 mg/ml at 20°C), alcohol. Slightly soluble in ether.

Applications

It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.

Notes

Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.

Literature References

J. M. Rubin-Preminger.; U. Englert. 3,4-Diamino­pyridine Acta Cryst. 2007, 63 (2),o757-o758 .

Jorge Molgó.; H?kan Lundh.; Stephen Thesleff. Potency of 3,4-Diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes. Eur. J. Pharmacol. 1980, 61 (1),25-34.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H330-H312-H319

Fatal if swallowed. Fatal if inhaled. Harmful in contact with skin. Causes serious eye irritation.

Precautionary Statements: P280h-P304+P340-P305+P351+P338-P320-P310-P302+P352

Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water.

Other References

Merck
14,2986
Beilstein
110232
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US7600000

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