Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A12481 Benzyl chloride, 99%, stab.

CAS Number
100-44-7
Synonyms
alpha-Chlorotoluene

Stock No. Size Price ($) Quantity Availability
A12481-36 500g 20.60
A12481-0E 2500g 83.90
A12481-0C 10000g 281.00
Add to Cart Bulk/Specialty Print Quote View Item

Benzyl chloride, 99%, stab.

MDL
MFCD00000889
EINECS
202-853-6

Chemical Properties

Formula
C7H7Cl
Formula Weight
126.59
Melting point
-43°
Boiling Point
178-180°
Flash Point
73°(163°F)
Density
1.099
Refractive Index
1.5380
Storage & Sensitivity
Ambient temperatures.
Solubility
Miscible with alcohol, ether. Insoluble in waterMiscible with alcohol, ether and chloroform.

Applications

Benzyl Chloride is used as an intermediate for manufacturing of benzyl alcohol, benzoic acid and benzyl cyanide. It is also used to prepare benzyl esters, which are used as plasticizer, flavorants and perfumes. It acts as an intermediate in the preparation of phenylacetic acid. In organic synthesis, it is used as an alkylating agent and utilized for the introduction of the benzyl protecting group for alcohols. Further, it is involved in the preparation of quaternary ammonium salts by reaction with tertiary amines. In addition to this, it is used to prepare Grignard reagent by reacting with metallic magnesium.

Notes

Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with common metals, lead,oxidizing agents, iron, iron salts, brass and aluminum

Literature References

Benzyllithium and substituted analogues have proved difficult to generate in a pure state owing to competing Wurtz coupling. Conditions have been described for efficient generation of benzyllithiums from the chlorides using Li naphthalenide in a mixed diethyl ether - THF - petroleum ether solvent system at -95o: J. Chem. Soc., Perkin 1, 185 (1995).

Amidocarbonylation with acetamide and a CO/H2 mixture under pressure, in the presence of Co2(CO)8 catalyst, provides a novel route to N-acetyl-DL-phenylalanine: J. Org. Chem., 61, 1842 (1996).

Lázaro, G.; Polo, V.; Fernández-Alvarez, F. J.; García-Orduña, P.; Lahoz, F. J.; Iglesias, M.; Pérez-Torrente, J. J.; Oro, L. A. Catalytic Hydrodechlorination of Benzyl Chloride Promoted by Rh-N-heterocyclic Carbene Catalysts. ChemSusChem 2015, 8 (3), 495-503.

Rodda, A. E.; Ercole, F.; Nisbet, D. R.; Forsythe, J. S.; Meagher, L. Optimization of Aqueous SI-ATRP Grafting of Poly(Oligo(Ethylene Glycol) Methacrylate) Brushes from Benzyl Chloride Macroinitiator Surfaces. Macromol. Biosci. 2015, 15 (6), 799-811.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H290-H302-H315-H317-H318-H331-H335-H336-H340-H350-H373

Combustible liquid. May be corrosive to metals. Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye damage. Toxic if inhaled. May cause respiratory irritation. May cause drowsiness or dizziness. May cause genetic defects. May cause cancer. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P201-P202-P210-P235-P260-P264b-P270-P271-P272-P280g-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P311-P330-P333+P313-P362-P370+P378q-P390-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation or rash occurs: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Absorb spillage to prevent material damage. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1129
Beilstein
471308
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2903.99
TSCA
Yes
RTECS
XS8925000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware