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A12488 O-Acetylsalicylic acid, 99%

CAS Number
50-78-2
Synonyms
2-Acetoxybenzoic acid

Stock No. Size Price ($) Quantity Availability
A12488-22 100g 20.60
A12488-36 500g 48.80
A12488-0E 2500g 167.00
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O-Acetylsalicylic acid, 99%

MDL
MFCD00002430
EINECS
200-064-1

Chemical Properties

Formula
C9H8O4
Formula Weight
180.15
Melting point
133-140°
Flash Point
250°(482°F)
Density
1.400
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Applications

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Notes

Store at room temperature. Ensure good ventilation.

Literature References

D W Gilroy et. Al. Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. Eur. J. Pharmacol. 1998, 355 (2-3),211-217.

K Schrör. Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Seminars in Thrombosis and Hemostasis. 1997, 23 (4),349-356.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H500

Harmful if swallowed. May form combustible dust concentrations in air

Precautionary Statements: P264b-P270-P301+P312-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,851
Beilstein
779271
Harmonized Tariff Code
2918.22
TSCA
Yes
RTECS
VO0700000

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