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It acts on type I calcium/calmodulin dependent phosphodiesterase and also a useful electron donor. Phenothiazine finds uses in metal free organic dye sensitizers, dyes and antioxidants.
A S Horn.; S H Snyder. Chlorpromazine and dopamine: conformational similarities that correlate with the antischizophrenic activity of phenothiazine drugs. PNAS. 1971, 68 (10),2325-2328.
Lea Assed Bezerra Silva et. al. Antimicrobial Photodynamic Therapy for the Treatment of Teeth with Apical Periodontitis: A Histopathological Evaluation. Journal of Endodontics. 2012, 38 (3),360-366.
Lithiation in THF gives orange crystals of (phenothiazin-10-yl)lithium.3THF. Carboxylation and the orientation of a second lithiation have been studied: Angew. Chem. Int. Ed., 34, 921 (1995).
Hazard Statements: H302-H317-H373
Harmful if swallowed. May cause an allergic skin reaction. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P264b-P270-P272-P280g-P301+P312-P302+P352-P314-P330-P333+P313-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant