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7378-99-6 - N,N-Dimethyl-n-octylamine, 95% - DMOA - N-n-Octyldimethylamine - A12546 - Alfa Aesar

A12546 N,N-Dimethyl-n-octylamine, 95%

CAS Number
7378-99-6
Synonyms
DMOA
N-n-Octyldimethylamine

Size Price ($) Quantity Availability
10g 27.81
50g 98.10
250g 391.50
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N,N-Dimethyl-n-octylamine, 95%

MDL
MFCD00009558
EINECS
230-939-3

Chemical Properties

Formula
CH3(CH2)7N(CH3)2
Formula Weight
157.30
Melting point
-57°
Boiling Point
195°
Flash Point
65°(149°F)
Density
0.765
Refractive Index
1.4243
Sensitivity
Air Sensitive
Solubility
Slightly miscible with water.

Applications

N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

Notes

Air sensitive. Incompatible with strong oxidizing agents, strong acids and copper.

Literature References

Modifier for reverse-phase liquid chromatographic separation of amines.

Matsukizono, H.; Endo, T. Synthesis of polyhydroxyurethanes from di(trimethylolpropane) and their application to quaternary ammonium chloride-functionalized films. RSC Adv. 2015, 5 (87), 71360-71369.

Matsunaga, H.; Haginaka, J. Separation of enantiomers on chiral stationary phase based on chicken alpha 1-acid glycoprotein: Effect of silica particle diameters on column performance. J. Chromatogr. A 2014, 1363, 96-100.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H314-H318-H227

Toxic if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.

Precautionary Statements: P210-P260-P280-P301+P310-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1698081
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2921.19
TSCA
Yes

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