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A12559 (+)-Quinidine

CAS Number
56-54-2
Synonyms

Stock No. Size Price ($) Quantity Availability
A12559-03 1g 21.20
A12559-06 5g 52.70
A12559-14 25g 190.00
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(+)-Quinidine

MDL
MFCD00135581
EINECS
200-279-0

Chemical Properties

Formula
C20H24N2O2
Formula Weight
324.42
Melting point
171-173°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in methanol, chloroform, alcohol (1 g/36ml), benzene and DMSO(100mM). Slightly soluble in ether and petroleum ether. Insoluble in water.

Applications

(+)-Quinidine is used to treat or prevent many types of irregular heartbeats (heart arrhythmias such as atrial fibrillation). It may also be used to treat malaria.

Notes

Light sensitive. Incompatible with oxidizing agents.

Literature References

Dan M.Roden, M.D.; Raymond L.Woosley, M.D., Ph.D.; R.Kirby Primm, M.D. Incidence and clinical features of the quinidine-associated long QT syndrome: Implications for patient care. American Heart Journal. 1986, 111, (6)1088-1093

 

Alain Borgeat, MD; Jean-Jacques Goy, MD; Raymond Maendly, MD; Urs Kaufmann, MD; MilanGrbic, MD; Ueli Sigwart, MD. Flecainide versus quinidine for conversion of atrial fibrillation to sinus rhythm. The American Journal of Cardiology. 1986, 58, (6)496-498

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H317

Toxic if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P261-P264b-P270-P272-P280g-P301+P310-P302+P352-P330-P333+P313-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8060
Beilstein
91866
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2939.20
TSCA
Yes
RTECS
VA4725000

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