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Lithiation with LDA occurs selectively on the side-chain. In a competitive study, the 2,3-dimethyl isomer was found to be attacked faster than the 2,6-isomer: J. Org. Chem., 48, 2130 (1983)./n
Hazard Statements: H226-H302-H315-H319-H335
Flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P260-P201-P280h-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.