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59-67-6 - Nicotinic acid, 99% - Niacin - Pyridine-3-carboxylic acid - A12683 - Alfa Aesar

A12683 Nicotinic acid, 99%

CAS Number
59-67-6
Synonyms
Niacin
Pyridine-3-carboxylic acid

Size Price ($) Quantity Availability
250g 24.60
1000g 62.62
5000g 213.60
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Nicotinic acid, 99%

MDL
MFCD00006391
EINECS
200-441-0

Chemical Properties

Formula
C6H5NO2
Formula Weight
123.11
Melting point
236-239°
Flash Point
293°(559°F)
Density
1.4
Solubility
Soluble in water. Slightly soluble in ethanol and ethyl ether. Insoluble in most lipid solvents.

Applications

Vitamin of the B complex with hypolipidemic properties occurring in various animal and plant tissues. Required by the body for the formation of coenzymes NAD and NADP.Nicotinic acid is used as an antidyslipidemic agent. It is also used to improve all lipoproteins well above the vitamin requirement and lowers the total cholesterol, "bad" LDL-cholesterol, and triglyceride levels. Further, it is used as a food additive in food industries, cosmetics and pharmaceuticals. In addition to this, it is used in medication, nutrient, enriched flours and in electroplating baths.

Notes

Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Cheng, X.; Hookway, E. S.; Kashima, T.; Oppermann, U.; Galione, A.; Athanasou, N. A. The Role of Calcium and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) in Human Osteoclast Formation and Resorption. Calcif. Tissue Int. 2015, 96 (1), 73-79.

Trabbic, C. J.; Zhang, F.; Walseth, T. F.; Slama, J. T. Nicotinic Acid Adenine Dinucleotide Phosphate Analogues Substituted on the Nicotinic Acid and Adenine Ribosides. Effects on ReceptorMediated Ca2+ Release. J. Med. Chem. 2015, 58 (8), 3593-3610.

GHS Hazard and Precautionary Statements

Hazard Statements: H319

Causes serious eye irritation.

Precautionary Statements: P280-P264-P305+P351+P338-P337+P313

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.

Other References

Merck
14,6525
Beilstein
109591
Harmonized Tariff Code
2936.29
TSCA
Yes
RTECS
QT0525000

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