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2-Bromo-3-hydroxypyridine is used to produce 2-bromo-4,6-diiodo-3-pyridinol. It is also used in azo dyes and in the synthesis of pterocellin A by reacting with kojic acid and in synthesis of orelline.
Parhi, A. K.; Xiang, A.; Bauman, J. D.; Patela, D.; Vijayan, R. S. K.; Das, K.; Arnold, E.; LaVoie, E. J. Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease. Bioorg. Med. Chem. 2013, 21 (21), 6435-6446.
Ganguly, N. C.; Mondal, P.; Roy, S.; Mitra, P. Ligand-free copper-catalyzed efficient one-pot access of benzo[b]pyrido[3,2-f][1,4]oxazepinones through O-heteroarylation-Smiles rearrangement-cyclization cascade. RSC Adv. 2014, 4 (98), 55640-55648.
Kato, Y.; Kawasaki, M.; Nigo, T.; Nakamur, S.; Fusano, A.; Teranishi, Y.; Ito, M. N.; Sumiyoshi, T. Identification of 2,3-disubstituted pyridines as potent, orally active PDE4 inhibitors. Bioorg. Med. Chem. 2013, 21 (18), 5851-5854.
Hazard Statements: H302-H312-H315-H319-H332
Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant