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1-Adamantanamine hydrochloride is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extra pyramidal reactions, and for postherpetic neuralgia. It is also used an NMDA-receptor antagoinst.
A.W. Galbraith; J.S. Oxford; G.C. Schild; G.I. Watson. Protective Effect Of 1-Adamantanamine Hydrochloride On Influenza A2 Infections In The Family Environment. The Lancet. 1969, 294(7629),1026-1028.
W. L. Davies; R. R. Grunert; R. F. Haff; J. W. McGahen; E. M. Neumayer; M. Paulshock; J. C. Watts; T. R. Wood; E. C. Hermann; C. E. Hoffmann. Antiviral Activity of 1-Adamantanamine (Amantadine). Science . 1964, 144(3620),862-863.
Hazard Statements: H302-H314-H335-H360
Harmful if swallowed. Causes severe skin burns and eye damage. May cause respiratory irritation. May damage fertility or the unborn child.
Precautionary Statements: P201-P202-P260-P264b-P270-P271-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant