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665-66-7 - 1-Adamantanamine hydrochloride, 99% - Amantadine hydrochloride - 1-Aminoadamantane hydrochloride - A12699 - Alfa Aesar

A12699 1-Adamantanamine hydrochloride, 99%

CAS Number
665-66-7
Synonyms
Amantadine hydrochloride
1-Aminoadamantane hydrochloride

Size Price ($) Quantity Availability
25g 56.65
100g 143.10
500g 599.40
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1-Adamantanamine hydrochloride, 99%

MDL
MFCD00074723
EINECS
211-560-2

Chemical Properties

Formula
C10H17N•HCl
Formula Weight
187.71
Melting point
360°
Sensitivity
Hygroscopic
Solubility
Soluble in water (50 mg/ml), ethanol (38 mg/ml at 25°C), chloroform (1:18), DMSO (38 mg/ml at 25°C), and methanol

Applications

1-Adamantanamine hydrochloride is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extra pyramidal reactions, and for postherpetic neuralgia. It is also used an NMDA-receptor antagoinst.

Notes

Hygroscopic. Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent and water/moisture.

Literature References

A.W. Galbraith; J.S. Oxford; G.C. Schild; G.I. Watson. Protective Effect Of 1-Adamantanamine Hydrochloride On Influenza A2 Infections In The Family Environment. The Lancet. 1969, 294(7629),1026-1028.

W. L. Davies; R. R. Grunert; R. F. Haff; J. W. McGahen; E. M. Neumayer; M. Paulshock; J. C. Watts; T. R. Wood; E. C. Hermann; C. E. Hoffmann. Antiviral Activity of 1-Adamantanamine (Amantadine). Science . 1964, 144(3620),862-863.

GHS Hazard and Precautionary Statements

Hazard Statements: H361-H302

Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Precautionary Statements: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,374
Beilstein
4198854
Harmonized Tariff Code
2921.30
TSCA
Yes
RTECS
AU4375000

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