Barium hydroxide octahydrate has been used in the centromeric heterochromatin banding technnique and to synthesize BaTiO3. The form Barium hydroxide was reported to catalyze the rate of β elimination of phosphoserine residues. It is also used as a general purpose additive for lubricants and greases, sugar fabrication, manufacturing soaps, fat saponification and chemical synthesis of other barium compounds.
Jay A. Young. Barium Hydroxide Octahydrate. J. Chem. Educ. 2006, 83(4), 539.
ngmar Persson; Magnus Sandström; Haruhiko Yokoyama. Structure of the Solvated Strontium and Barium Ions in Aqueous, Dimethyl Sulfoxide and Pyridine Solution, and Crystal Structure of Strontium and Barium Hydroxide Octahydrate. Zeitschrift für Naturforschung A. 1995, 50(1), 21-37.
Preferred base for the Horner-Wadsworth-Emmons reaction with sensitive aldehydes, such as in formation of complex (E)-enones in natural product synthesis: Synlett, 774 (1993).
Suzuki coupling of 4-iodopyridines with arylboronic acids is promoted by this base which has advantages for sterically hindered substrates: J. Organomet. Chem., 517, 25 (1996).
For a brief feature on uses of the reagent, see: Synlett, 1739 (2002).
Hazard Statements: H302-H332-H314-H318
Harmful if swallowed. Harmful if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280i-P304+P340-P405-P501a
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.