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2-n-Butylthiophene is an inhibitor of DMH-induced aberrant crypt formation. It is used as a Glutathione S-transferase inducer. It Inhibits tumorigenesis in vivo. It is used as a primary and secondary intermediate.
LKT Lam.; BL Zheng. Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo [a] pyrene-induced lung and forestomach tumorigenesis in A/J mice. Nutrition and Cancer. 1992 17, (1) , 19-26.
J Roger.; F Pogan.; H Doucet. Ligand-less palladium-catalyzed direct 5-arylation of thiophenes at low catalyst loadings. Green Chemistry. 2009 11, (3) , 425-432.
Hazard Statements: H226
Flammable liquid and vapour.
Precautionary Statements: P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant