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94-09-7 - Ethyl 4-aminobenzoate, 98% - H-4-Abz-OEt - 4-Aminobenzoic acid ethyl ester - A12754 - Alfa Aesar

A12754 Ethyl 4-aminobenzoate, 98%

CAS Number
94-09-7
Synonyms
H-4-Abz-OEt
4-Aminobenzoic acid ethyl ester

Size Price ($) Quantity Availability
250g 46.14
1000g 135.96
5000g 415.20
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Ethyl 4-aminobenzoate, 98%

MDL
MFCD00007892
EINECS
202-303-5

Chemical Properties

Formula
C9H11NO2
Formula Weight
165.19
Melting point
88-92°
Boiling Point
310°
Flash Point
>110°(230°F)
Solubility
Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water

Applications

Ethyl 4-aminobenzoate is used as an anesthetic and utilized for topical pain reliever. It is mixed with antipyrine to get A/B otic drops, which is used in the removal of earwax as well as relieve ear from pain. It exhibits analgesic and antipruritic effect mainly used for wounds, ulcers, mucosal surfaces and hemorrhoids narcotic pain. Further, it is a main constituent of anesthetic ointments. In addition to this, it is effective to toothache, sore throat, oral ulcers, hemorrhoids and anal fissure.

Notes

Incompatible with strong oxidizing agents, reducing agents, acids and bases.

Literature References

Warnke, S.; Seo, J.; Boschmans, J.; Sobott, F.; Scrivens, J. H.; Bleiholder, C.; Bowers, M. T.; Gewinner, S.; Schöllkopf, W.; Pagel, K.; von Helden, G. Protomers of Benzocaine: Solvent and Permittivity Dependence. J. Am. Chem. Soc. 2015, 137 (12), 4236-4242.

Alotaibi, M. R.; Husbands, S. M.; Blagbrough, I. S. 1H, 13C, 15N HMBC, and 19F NMR spectroscopic characterisation of seized flephedrone, cut with benzocaine. J. Pharm. Biomed. Anal. 2015, 107, 535-538.

GHS Hazard and Precautionary Statements

Hazard Statements: H319-H317

Causes serious eye irritation. May cause an allergic skin reaction.

Precautionary Statements: P261-P280-P264-P305+P351+P338-P363-P321-P333+P313-P337+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1086
Beilstein
638434
Harmonized Tariff Code
2922.49
TSCA
Yes
RTECS
DG2450000

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