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Ethyl 4-aminobenzoate is used as an anesthetic and utilized for topical pain reliever. It is mixed with antipyrine to get A/B otic drops, which is used in the removal of earwax as well as relieve ear from pain. It exhibits analgesic and antipruritic effect mainly used for wounds, ulcers, mucosal surfaces and hemorrhoids narcotic pain. Further, it is a main constituent of anesthetic ointments. In addition to this, it is effective to toothache, sore throat, oral ulcers, hemorrhoids and anal fissure.
Warnke, S.; Seo, J.; Boschmans, J.; Sobott, F.; Scrivens, J. H.; Bleiholder, C.; Bowers, M. T.; Gewinner, S.; Schöllkopf, W.; Pagel, K.; von Helden, G. Protomers of Benzocaine: Solvent and Permittivity Dependence. J. Am. Chem. Soc. 2015, 137 (12), 4236-4242.
Alotaibi, M. R.; Husbands, S. M.; Blagbrough, I. S. 1H, 13C, 15N HMBC, and 19F NMR spectroscopic characterisation of seized flephedrone, cut with benzocaine. J. Pharm. Biomed. Anal. 2015, 107, 535-538.
Hazard Statements: H315-H317-H319
Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation.
Precautionary Statements: P261-P264b-P272-P280-P302+P352-P305+P351+P338-P333+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant