Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A12881 Isopropyltriphenylphosphonium iodide, 98+%

CAS Number
24470-78-8
Synonyms
(2-Propyl)triphenylphosphonium iodide

Stock No. Size Price ($) Quantity Availability
A12881-09 10g 34.40
A12881-22 100g 253.00
A12881-30 250g 528.00
Add to Cart Bulk/Specialty Print Quote View Item

Isopropyltriphenylphosphonium iodide, 98+%

MDL
MFCD00031595
EINECS
246-281-5

Chemical Properties

Formula
(CH3)2CHP(C6H5)3I
Formula Weight
432.29
Melting point
195-198°
Storage & Sensitivity
Hygroscopic. Light Sensitive. Ambient temperatures.
Solubility
Solubility in methanol, very faint turbidity.

Applications

Useful precursor of isopropylidene unit by Wittig reaction with aldehydes. It is also used in tandem cyclopropanation and Wittig olefination in a synthesis of chrysanthemic acid. Also employed in Wittig and cyclopropanation reactions. It is used as a reactant for total synthesis of heliananes, in the preparation of highly substituted benzene derivatives, synthesis of curcuphenol and elvirol analogs via a retro-aldol reaction as fungicidal agents, 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents.

Notes

Light sensitive and hygroscopic. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Richard A. Bartsch, et. al. Synthesis of highly lipophilic crown ether carboxylic acids.J Org Chem.,1983,48(25), 4864-4869.

Hiroshi Yamataka, et al. Mechanistic study of the Wittig reaction of benzophenone with a nonstabilized ylide.J. Org. Chem.,1988,53(16), 3877-3879.

Useful precursor of isopropylidene unit by Wittig reaction with aldehydes: J. Am. Chem. Soc., 103, 2823 (1981), and ketones: J. Org. Chem., 53, 3877 (1988).

The derived phosphorane can also add to activated double bonds to give gem-dimethyl cyclopropanes: Tetrahedron Lett., 3781 (1972). For use of tandem cyclopropanation and Wittig olefination in a synthesis of chrysanthemic acid, see: Tetrahedron Lett., 3911 (1976):

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P305+P351+P338-P314-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical advice/attention if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3599629
Harmonized Tariff Code
2931.39
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware