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MOPS is mainly used in biological experiments as a buffer solution. It is also used in protein purification. Further, it is utilized for polyacrylamide gel electrophoresis.
Biological buffer, pKa = 7.2 at 20oC: Biochemistry, 5, 467 (1966). Utilized to promote a mimetic of the transketolase reaction: Eur. J. Org. Chem., 1121 (2006).
Roy, L. N.; Roy, R. N.; Allen, K. A.; Mehrhoff, C. J.; Henson, I. B.; Stegner, J. M. Buffer standards for the physiological pH of the zwitterionic compound of 3-(N-morpholino) propanesulfonic acid (MOPS) from T=(278.15 to 328.15) K. J. Chem. Thermodyn. 2012, 47, 21-27.
EL-Gahami, M. A.; Al-Bogami, A. S.; Albishri, H. M. Medium effect on the dimethyltin(IV) complexes of 2-(N-morpholino) ethanesulfonic and 3-(N-morpholino) propanesulfonic acid. J. Mol. Liq. 2014, 193, 45-50.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant