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62-50-0 - Ethyl methanesulfonate, 99% - Ethyl mesylate - Methanesulfonic acid ethyl ester - A12938 - Alfa Aesar

A12938 Ethyl methanesulfonate, 99%

CAS Number
62-50-0
Synonyms
Ethyl mesylate
Methanesulfonic acid ethyl ester

Size Price ($) Quantity Availability
5g 26.37
10g 46.69
50g 143.17
250g 516.60
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Ethyl methanesulfonate, 99%

MDL
MFCD00007559
EINECS
200-536-7

Chemical Properties

Formula
CH3SO3CH2CH3
Formula Weight
124.16
Boiling Point
85-86°/10mm
Flash Point
100°(212°F)
Density
1.170
Refractive Index
1.4180
Sensitivity
Moisture Sensitive
Solubility
Miscible with water.

Applications

Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.

Notes

Special handling precautions required. View MSDS prior to purchase. MSDS available online at www.alfa.com.Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.

Literature References

Hartwig, B.; James, G. V.; Konrad, K.; Schneeberger, K.; Turck, F. Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks. Plant Physiol. 2012, 160 (2), 591-600.

Gunther, W. C.; Coffing, S. L.; Dickinson, D. A.; Engel, M. E.; Fiedler, R. D.; O'Lone, S. D.; Dobo, K. L. Evaluation of the Pig-a, micronucleus, and comet assay endpoints in a 28-day study with ethyl methanesulfonate. Environ Mol Mutagen 2014, 55 (6), 492-499.

GHS Hazard and Precautionary Statements

Hazard Statements: H340-H351-H361-H302

May cause genetic defects. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Precautionary Statements: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3827
Beilstein
773969
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2904.10
TSCA
Yes
RTECS
PB2100000

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