Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A12947 Cerium(III) chloride heptahydrate, 99%

CAS Number
Cerous chloride heptahydrate

Stock No. Size Price ($) Quantity Availability
A12947-18 50g 32.80
A12947-30 250g 103.00
A12947-0B 1000g 332.00
Add to Cart Add to Quote Request View Item

Cerium(III) chloride heptahydrate, 99%


Chemical Properties

Formula Weight
372.60 (246.48anhy)
Storage & Sensitivity
Hygroscopic. Air Sensitive. Store under Argon. Ambient temperatures.
Soluble in alcohol, water, and acetone. Slightly soluble in tetrahydrofuran.


Cerium(III) chloride heptahydrate is used in the preparation of allylsilanes from esters. It is used as a reducing agent in organic synthesis in place of sodium borohydride. In Luche reaction, carvone gives selectively allylic alcohol.


Air sensitive. Hygroscopic. Incompatible with strong acids and strong oxidizing agents.

Literature References

Reagent for selective cleavage of MEM ethers (see 2-Methoxyethoxymethyl­ chloride, L01050 ) under mild conditions: Org. Lett., 3, 1149 (2001).

Useful in modifying the reactivity of Sodium borohydride, 35788 , allowing selective reduction of ketones in the presence of aldehydes: J. Am. Chem. Soc., 101, 5848 (1979), and giving increased selectivity for 1,2-reduction of enones to allylic alcohols: J. Chem. Soc., Chem. Commun., 601 (1978); cyclohexenones can be reduced in an alkyl alcohol to give the alkyl allylic ether in high yield: Pol. J. Chem., 69, 1655 (1995).

With a catalytic amount of NaI in acetonitrile, dioxolanes (ethylene acetals) are deprotected to the parent carbonyl compounds: J. Org. Chem., 62, 4183 (1997), as are 4-methoxybenzyl ethers: J. Org. Chem., 64, 5696 (1999), and allyl ethers: Tetrahedron Lett., 40, 7293 (1999), to the parent alcohols. With a stoichiometric amount of NaI, alcohols can be converted to alkyl iodides: J. Org. Chem., 65, 2830 (2000), aryl alkyl ethers undergo dealkylation to phenols: Chem. Lett., 738 (2000), and selective deprotection of N-Boc protected tert-butyl amino acid esters can be achieved: J. Org. Chem., 66, 4430 (2001). Also deprotects the tert-butyl ethers of alcohols: Adv. Synth. Catal., 348, 905 (2006). For a review of the CeCl3•nH2O/NaI system,as an efficient, water-tolerant Lewis Acid promoter in organic synthesis, see: Synlett, 2101 (2003).

In combination with Zn in acetonitrile, promotes the Reformatsky reaction of Ethyl­ bromofluoroacetate, B21579 : J. Org. Chem., 67, 72 (2002).

For preparation of the anhydrous reagent and its use in combination with organolithium or Grignard reagents to suppress side reactions with carbonyl compounds, see: Org. Synth., 76, 228 (1998).

For a brief feature on uses of this reagent, see: Synlett, 1935 (2002).

Li, B.; Shao, X.; Hao, Y.; Zhao, Y. Ultrasonic-spray-assisted synthesis of metal oxide hollow/mesoporous microspheres for catalytic CO oxidation. RSC Adv. 2015, 5 (104), 85640-85645.

Ogata, T.; Narita, H.; Tanaka, M. Adsorption behavior of rare earth elements on silica gel modified with diglycol amic acid. Hydrometallurgy 2015, 152, 178-182.

GHS Hazard and Precautionary Statements

Hazard Statements: H314

Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
Packing Group
Harmonized Tariff Code


  • A10324

    Bisphenol A, 97+%
  • A12005

    Pyridine, 99+%
  • 11193

    Ytterbium(III) chloride hydrate, REacton®, 99.9% (REO)
  • 11329

    Cerium(III) nitrate hexahydrate, REacton®, 99.5% (REO)
  • 12104

    Zirconium(IV) chloride, Reactor Grade, 99.5+% (metals basis)

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware