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Phloroglucinol dihydrate is utilized in the preparation of active pharmaceutical ingredients such as flopropione. It acts as a reagent for the Tollens test for pentoses. It is mixed with hydrochloric acid and plays an important role for the detection of lignin (Wiesner test). It is involved in the analysis and qualitative detection of free hydrochloric acid in gastric juice by using Gunzburg reagent. Further, it serves as a coupling agent in printing. It is also employed as a reagent for pentoses, pentosans, aldehydes and as a decalcifier of bone specimens in microscopy.
Cheng, C.; Liu, C.; Gu, Y. One-pot three-component reactions of methyl ketones, phenols and a nucleophile: an expedient way to synthesize densely substituted benzofurans. Tetrahedron 2015, 71 (42), 8009-8017.
Qin, W.; Lü, H.; Xie, Z. Preparation and evaluation of o-phenanthroline immobilized on a hybrid silica monolith modified with ionic liquids for reversed-phase pressurized capillary electrochromatography. J. Sep. Sci. 2014, 37 (24), 3722-3728.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.