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2-Iodoaniline is used as an intermediate in organic synthesis.
Gozen Bereket; Evrim Hur; Yucel Sahin. Electrodeposition of polyaniline, poly(2-iodoaniline), and poly(aniline-co-2-iodoaniline) on steel surfaces and corrosion protection of steel. Applied Surface Science. 2005, 252, (5),1233-1244
Qiuping Ding; Banpeng Cao; Xianjin Liu; Zhenzhen Zongand; Yi-Yuan Peng. Synthesis of 2-aminobenzothiazole via FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water. Green Chemistry. 2010, (9),1607-1610
Quinolines may be synthesized by Pd-catalyzed reaction with allyl alcohols: Tetrahedron Lett., 32, 569 (1991).
Reacts with unsymmetrical acetylenes in the presence of Palladium(II) acetate, 10516, to give indoles substituted at the 2- and/or 3-positions: J. Am. Chem. Soc., 113, 6689 (1991):
Under similar conditions, ketones with an ɑ-methylene group also give indole derivatives: J. Org. Chem., 62, 2676 (1997).
Hazard Statements: H302-H312-H315-H319-H332-H335
Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant